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PDB Keyword
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PF01958

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary
    Live PFAM
    Name: Accession: PF01958 (PFAM live)
    # sequence matches: # architectures:
    # taxonomy ids: PDB:  1h2h1j5p2dc1
    GO Terms
    GO:0019363 pyridine nucleotide biosynthetic process process
    GO:0006742 NADP catabolic process process
    GO:0055114 oxidation reduction process
    GO:0016491 oxidoreductase activity function
      

    Resources
    Pfam ID: DUF108 PDB: 1h2h_A
    Solved by: JCSG    
    FFAS:(view)
      Top FFAS hit in PDB: "1j5pA, ASPARTATE DEHYDROGENASE" No significant hits in Pfam.
    Meta-Basic:
      Top significant hit (PDB90): "1j5pA, oxidoreductase ; crystal structure of aspartate dehydrogenase (tm1643) from thermotoga maritima at 1.9 a resolution "
    CATH: CATH Domain E-value CATH Node
      1j5pA02 3.40E-25 3.30.360.10
    FUNFAM (eval=0 ): L-aspartate dehydrogenase -like
    PUBSERVER: (view)
      Publications(s) found: 180
      Publications(s) meeting filtering criteria: 3
    GeneSilico Metaserver
      PDBBLAST PDB: 1j5p_A ECC: 1.4.3.16
      FFAS PDB: 1j5p_A ECC: 1.4.3.16
      PRC PDB: 1j5p_A ECC: 1.4.3.16
      SPARKS PDB: 1j5p_A ECC: 1.4.3.16
      BLASTP PDB: 2dc1_A SCOP : predicted d.81.1 ECC: 1.4.1.21
      HHBLITS PDB: 1j5p_A ECC: 1.4.3.16
      COMPASS PDB: 2dc1_A SCOP : predicted d.81.1 ECC: 1.4.1.21
      COMA PDB: 1j5p_A ECC: 1.4.3.16
      CSBLAST PDB: 1j5p_A ECC: 1.4.3.16
      HHSEARCH PDB: 1j5p_A ECC: 1.4.3.16

    Topsan Members

    Tag pages as 'PF01958' to appear in this list.

    Name Annotation Author(s)
    1j5p
     The gene TM1643 from Thermotoga maritima encodes an enzyme aspartate dehydrogenase EC:1.4.1.21 COG:COG0136.  The structure of this enzyme has been previously solved PDB:1H2H [Ref].  TM1643 is found i... anton (3 edits)
    pascual (2 edits)
    kellrott (1 edits)

    Summary

    Pfam family PFAM:PF01958 {Domain of unknown function DUF108} with 223 members in NR database and additional 111 members in the metagenomic datasets is represented in Archaea, Bacteria, and Eukaryota. The first structural representative solved (PDB Id: TOPSAN:1j5p) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1diha2 classified as Fwde/GAPDH domain-like fold. Based on Ligand one can argue that this family is remotely homologous to previously known structures from 'd1diha2' this fold. Based on fold and evidence of homology, ligands one can hypothesize that this family is oxidoreductases, aspartate dehydrogenases

    Reviews

    References

     

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