.
The Open Protein Structure Annotation Network
PDB Keyword
.

PF04296

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary
    3. 3. References

    Live PFAM
    Name: Accession: PF04296 (PFAM live)
    # sequence matches: # architectures:
    # taxonomy ids: PDB:  1g2r
      

    Resources
    Pfam ID: DUF448 PDB: 1g2r_A
    Solved by: MCSG    
    FFAS:(view)
      Top FFAS hit in PDB: "1g2rA, HYPOTHETICAL CYTOSOLIC PROTEIN" No significant hits in Pfam.
    Meta-Basic:
      Top significant hit (PDB90): "1g2rA, structural genomics, unknown function ; hypothetical cytosolic protein coded by gene from nusa/infb, ylxr homologue "
    CATH: CATH Domain E-value CATH Node
      1g2rA00 1.90E-29 3.30.1230.10
    PUBSERVER: (view)
      Publications(s) found: 762
      Publications(s) meeting filtering criteria: 4
    GeneSilico Metaserver
      PDBBLAST PDB: 1g2r_A SCOP : d.192.1.1
      FFAS PDB: 1g2r_A SCOP : d.192.1.1
      MGENTHREADER PDB: 1g2r_A SCOP : d.192.1.1
      PRC PDB: 1g2r_A SCOP : d.192.1.1
      SPARKS PDB: 1g2r_A SCOP : d.192.1.1
      BLASTP PDB: 1g2r_A SCOP : d.192.1.1
      HHBLITS PDB: 1g2r_A SCOP : d.192.1.1
      COMPASS PDB: 1g2r_A SCOP : d.192.1.1
      COMA PDB: 1g2r_A SCOP : d.192.1.1
      CSBLAST PDB: 1g2r_A SCOP : d.192.1.1
      HHSEARCH PDB: 1g2r_A SCOP : d.192.1.1

    Topsan Members

    Tag pages as 'PF04296' to appear in this list.

    Name Annotation Author(s)
    1g2r

    Summary

    Pfam family PFAM:PF04296 {Protein of unknown function (DUF448)} with 602 members in NR database and additional 314 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id: TOPSAN:1g2r) was subject to FATCAT structural similarity search that yielded no results, thus supporting and earlier classification as a novel fold [Ref]. Based on sequence and structure analysis/ original paper one can hypothesize that this family is it is proposed that YlxR is an RNA-binding protein.

    Genomic context suggest this protein could be related to translation as it can be often found in chromosomal clusters with translation factors (infB, rbfA). In 51 out of ~1500 cases, this domain is fused to the ribosomal protein domain (PF01248) indication it can be involved in translation.

    Reviews

    References

     

    1. (No Results)

       


      Discuss this publication
    Tag page

    Files (0)

     
    You must login to post a comment.
    All content on this site is licensed under a Creative Commons Attribution 3.0 License
    Powered by MindTouch