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The Open Protein Structure Annotation Network
PDB Keyword
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PF04445

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary
    Live PFAM
    Name: Accession: PF04445 (PFAM live)
    # sequence matches: # architectures:
    # taxonomy ids: PDB:  2oyr2pgx2pkw2r6z
      

    Topsan Members

    Tag pages as 'PF04445' to appear in this list.

    Name Annotation Author(s)
    2oyr

    Summary

    Pfam family PFAM:PF04445 {Protein of unknown function (DUF548)} with 460 members in NR database and additional 301 members in the metagenomic datasets is represented in Bacteria, and Eukaryota. The first structural representative solved (PDB Id: TOPSAN:2oyr) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1ws6a1 classified as S-adenosyl-L-methionine-dependent methyltransferase fold. (Note: additional/lacking secondary structure elements). Profile-profile methods confirm remote homology between this family and superfamily of S-adenosyl-L-methionine-dependent methyltransferases; fold of the same name. Based on remote homology confirmed by the structure, ligand one can hypothesize that this family is probably involved in transfer of methyl group

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