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The Open Protein Structure Annotation Network
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PF04524

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary
    Live PFAM
    Name: Accession: PF04524 (PFAM live)
    # sequence matches: # architectures:
    # taxonomy ids: PDB: 
      

    Topsan Members

    Tag pages as 'PF04524' to appear in this list.

    Name Annotation Author(s)
    2p5z
    The structure of the N-terminus of E. coli c3393 (VgrG) comprises 3 components of a type VI secretion system (T6SS) used by gram negative bacteria, which share structural similarity to bacteriophage ... msauder (2 edits)

    Summary

    Pfam family PFAM:PF04524 {Protein of unknown function, DUF586} with 717 members in NR database and additional 101 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id: TOPSAN:2p5z) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1wthd1 classified as Phage tail proteins fold. (Note: additional/lacking secondary structure elements). Based on indirect marginal prediction from FFAS which uses a sequence of another phage tail structure of 3cdd as an intermedadiate then confirmed by structural similarity one can argue that this family is remotely homologous to previously known structures from 'd1wthd1' this fold. Based on remote homology confirmed by structural similarity one can hypothesize that this family is phage assembly proteins

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