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The Open Protein Structure Annotation Network
PDB Keyword
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PF06821

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary
    3. 3. References
    Live PFAM
    Name: Accession: PF06821 (PFAM live)
    # sequence matches: # architectures:
    # taxonomy ids: PDB:  1uxo2qs93bdv
      

    Topsan Members

    Tag pages as 'PF06821' to appear in this list.

    Name Annotation Author(s)
    1uxo

    Summary

    Pfam family PFAM:PF06821 {Alpha/Beta hydrolase family of unknown function (DUF1234)} with 330 members in NR database and additional 85 members in the metagenomic datasets is represented in Bacteria, and Eukaryota. The first structural representative solved (PDB Id: TOPSAN:1uxo) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1jfra_ classified as Alpha/beta hydrolase fold. Profile-profile methods confirm remote homology between this family and superfamily of alpha/beta hydrolase; fold of the same name. Based on sequence and structure analysis/ original paper one can hypothesize that this family is it is very likely that YdeN is a carboxylesterase active on a water-soluble ester in which the substrate, possibly the acyl group, has a hydrophobic nature.

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