The Open Protein Structure Annotation Network
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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Structure of aspartoacylase, the brain enzyme impaired in Canavan disease. Proc.Natl.Acad.Sci.Usa 104 456-461 2007
    Site CESG
    PDB Id 2gu2 Target Id GO.59616
    Molecular Characteristics
    Source Rattus norvegicus
    Alias Ids TPS30246, Molecular Weight 35311.67 Da.
    Residues 312 Isoelectric Point 5.95
    Sequence mtscvaeepikkiaifggthgneltgvflvthwlkngaevhraglevkpfitnpravekctryidcdln rvfdlenlskemsedlpyevrraqeinhlfgpknsddaydvvfdlhnttsnmgctliledsrndfliqm fhyiktcmaplpcsvyliehpslkyattrsiakypvgievgpqphgvlradildqmrrmlkhaldfiqr fnegkefppcaidvykimekvdyprnesgdvaavihpnlqdqdwkplhpgdpvfvsldgkviplggdct vypvfvneaayyekkeafakttkltlnaksirstlh
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 2
    Resolution (Å) 1.80 Rfree 0.194
    Matthews' coefficent 2.33 Rfactor 0.1494
    Waters 552 Solvent Content 47.27

    Ligand Information
    Ligands SO4 (SULFATE) x 5
    Metals ZN (ZINC) x 2



    Protein Summary

    Ligand Summary




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