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1vku

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of Acyl carrier protein (TM0175) from Thermotoga maritima at 2.00 A resolution. To be published
    Site JCSG
    PDB Id 1vku Target Id 282055
    Molecular Characteristics
    Source Thermotoga maritima msb8
    Alias Ids TPS1189,TM0175 Molecular Weight 10284.21 Da.
    Residues 88 Isoelectric Point 4.33
    Sequence merkkliakfveiasekmgkdletvdeentfkelgfdsidvidlvmffedefalriedeeiskirkvkd lidivikkleeiddevseg
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 1
    Resolution (Å) 2.00 Rfree 0.25276
    Matthews' coefficent 2.14 Rfactor 0.19696
    Waters 45 Solvent Content 42.14

    Ligand Information
    Ligands
    Metals

    Jmol

     
    Google Scholar output for 1vku
    1. The Buccaneer software for automated model building. 1. Tracing protein chains
    K Cowtan - Acta Crystallographica Section D: Biological , 2006 - scripts.iucr.org
     
    2. Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain
    EJ Drake, DA Nicolai, AM Gulick - Chemistry & biology, 2006 - Elsevier
     
    3. Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation_site sequence
    MA Johnson, W Peti, T Herrmann, IA Wilson - Protein , 2006 - Wiley Online Library
     
    4. StructureFunction Analysis of the Acyl Carrier Protein Synthase (AcpS) from Mycobacterium tuberculosis
    O Dym, S Albeck, Y Peleg, A Schwarz - Journal of molecular , 2009 - Elsevier
     
    5. Solution Structure of 4 -Phosphopantetheine-GmACP3 from Geobacter metallireducens: A Specialized Acyl Carrier Protein with Atypical Structural Features and a
    TA Ramelot, MJ Smola, HW Lee, C Ciccosanti - Biochemistry, 2011 - ACS Publications
     
    6. Performance of phased rotation, conformation and translation function: accurate protein model building with tripeptidic and tetrapeptidic fragments
    F Pavelcik, J Vaclavik - Acta Crystallographica Section D: Biological , 2010 - scripts.iucr.org
     

    Protein Summary

    The TM0175 gene from Thermotoga maritima encodes an acyl-carrier protein (ACP) (PF00550, COG0236, EC).

     

    The structure shows strong similarity to the oxytetracycline polyketide synthase ACP from Streptomyces rimosus (PDB id: 1nq4, Findlow 2003) with

    Ligand Summary



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