The Open Protein Structure Annotation Network
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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structure of SusD homolog (NP_813570.1) from Bacteroides thetaiotaomicron VPI-5482 at 1.70 A resolution. To be Published
    Site JCSG
    PDB Id 3ihv Target Id 396218
    Molecular Characteristics
    Source Bacteroides thetaiotaomicron vpi-5482
    Alias Ids TPS25893,NP_813570.1, BIG_773, 326125 Molecular Weight 60914.67 Da.
    Residues 534 Isoelectric Point 5.34
    Sequence eetrtevekknymnnaeeakdvllgvyrtntldamygyylsilfnlgtdisqvegsgnenfriiptnsf pttqsevqqtwaalytgiyrandflerisnkigsytttdkklatlyiaearalrgmfyfelvrrfgnvv lmtstqmsnqnpatyvqsapekvyeyieddllyacdilpyatddqyresndyrfskgaalglltkvyat wagypvkdeskweaaaktarilvesgkhgllkdyeqlwkntcngtwdpteslieisfysptvsgnsdpv grigkwngvkttaiagvrgscaanvkvvhtfvldwredvsdirrdlsianyqytdtkkslwvagasdtd esaaekdadptkaqknkqnytpakwdiqkyvttnsfinndksnvnwyflryadvlllyaealnewkhgp daeaynainavrrrgygnpsntsacdlpqgldetsfreavrkersyelsfeghrrqdlirwgiyyktvq atakelgywwegtgspnysvatyteegkhelfpipqrdmdlciqfnqnpkw
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 2
    Resolution (Å) 1.70 Rfree 0.193
    Matthews' coefficent 2.42 Rfactor 0.162
    Waters 1251 Solvent Content 49.20

    Ligand Information


    Google Scholar output for 3ihv
    1. Structure of the C_terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex
    P Sampathkumar, T Gheyi, SA Miller - Proteins: Structure, , 2011 - Wiley Online Library
    2. Glycan recognition by the Bacteroidetes Sus-like systems
    DN Bolam, NM Koropatkin - Current Opinion in Structural Biology, 2012 - Elsevier

    Protein Summary

    This protein is now in family PF07980.4 SusD CL0020 along with other structures.


    The x-ray crystal structure of target ID 396218 has been determined at a resolution of 1.7 Angstroms using Se-multiwavelength anomalous disperson methods. A search of the Pfam A database using the amino acid sequence shows that the C-terminal end of target ID 396218 (residues 260-534) contains a domain that belongs to theSusD_RagB (PF07980) Pfam group. Shown below is a ribbons representation of the structure of target ID 396218 color coded with the N-terminal region in blue and the C-terminal region in red.



    Proteins from this family, present in all Bacteroidetes, in most of them in large groups of paralogs, are secreted and anchored in the outer membrane, where they become members of the polysaccharide binding/processing unit. Recently, the structures for several SusD proteins from human gut symbiotic bacteria have been reported by JCSG. Target ID 396218 represents the seventh SusD structure reported by JCSG.These related structures include PDB ID 3hdx, PDB ID 3gzs, PDB ID 3g8y, PDB ID 3fdh, PDB ID 3ejn, and PDB ID 3cgh.


    Ligand Summary




    No references found.

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