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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structure of Putative dihydrofolate reductase (YP_001636057.1) from CHLOROFLEXUS AURANTIACUS J-10-FL at 1.50 A resolution. To be published
    Site JCSG
    PDB Id 3kgy Target Id 394390
    Molecular Characteristics
    Source Chloroflexus aurantiacus j-10-fl
    Alias Ids TPS27855,YP_001636057.1, _0052.000516_, 326853 Molecular Weight 23836.07 Da.
    Residues 212 Isoelectric Point 6.66
    Sequence mskvfvnislsldgfmapegmdmahfsdptyknwgakwgalmawalsqqylreklklgtggetgpvndm vrhtfertgahimgkrmfeggergwpeeapfhtpvyvltherrnpwvrpggttfyfvndgpeqalalar eaagerdirisgganviqqylnlglvdeleialipvifgggrrlfenlheplpqfridrvlasptathl ryvrl
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 2
    Resolution (Å) 1.50 Rfree 0.174
    Matthews' coefficent 2.10 Rfactor 0.149
    Waters 566 Solvent Content 41.38

    Ligand Information


    Google Scholar output for 3kgy
    1. Quantifying instrument errors in macromolecular X-ray data sets
    K Diederichs - Acta Crystallographica Section D: Biological , 2010 - scripts.iucr.org
    2. Structural-based analysis of dihydrofolate reductase evolution
    D Hecht, J Tran, GB Fogel - Molecular Phylogenetics and Evolution, 2011 - Elsevier

    Protein Summary

    Pfam: this protein is now in family PF01872,  containing 10 RibD_C CL0387 along with other structures.



    Target ID 394390 belongs to the RibD C-terminal domain (PF01872) Pfam A family. The structural basis for this Pfam class has been investigated, with 8 structures deposited for the family in the PDB.  Shown below is a ribbon representation of the structure color-coded with the N-terminus in blue and the C-terminus in red. The structure was determined to a resolution of 1.50 Angstroms using three wavelength Se-multiwavelength anomalous dispersion. The structure of target ID 394390 is similar to those belonging to the Dihydrofolate reductase. 



    Ligand Summary




    No references found.

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    754.25 kB22:57, 30 Sep 2009kevinjinActions
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