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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Ligand-induced Conformational Changes and a Reaction Intermediate in Branched-chain 2-Oxo Acid Dehydrogenase (E1) from Thermus thermophilus HB8, as Revealed by X-ray Crystallography. J.Mol.Biol. 337 1011-1033 2004
    Site RSGI
    PDB Id 1umb Target Id ttk003000456.2
    Molecular Characteristics
    Source Thermus thermophilus
    Alias Ids TPS14366, Molecular Weight 35090.64 Da.
    Residues 324 Isoelectric Point 5.86
    Sequence malmtmvqalnraldeemakdprvvvlgedvgkrggvflvtegllqkygpdrvmdtplseaaivgaalg maahglrpvaeiqfadyifpgfdqlvsqvaklryrsggqftaplvvrmpsgggvrgghhhsqspeahfv htaglkvvavstpydakgllkaairdedpvvflepkrlyrsvkeevpeedytlpigkaalrregkdltl igygtvmpevlqaaaelakagvsaevldlrtlmpwdyeavmnsvaktgrvvlvsdaprhasfvsevaat iaedlldmllappirvtgfdtpypyaqdklylptvtrilnaakraldy
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 2
    Resolution (Å) 2.10 Rfree 0.194
    Matthews' coefficent 3.23 Rfactor 0.169
    Waters 1164 Solvent Content 61.65

    Ligand Information
    Ligands TDP (THIAMIN) x 2
    Metals MG (MAGNESIUM) x 2

    Jmol

     

    Protein Summary


    Ligand Summary

    Reviews

    References

     

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