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The Open Protein Structure Annotation Network
PDB Keyword
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2d0t

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase. Proc.Natl.Acad.Sci.Usa 103 2611-2616 2006
    Site RSGI
    PDB Id 2d0t Target Id my_001000021.1
    Molecular Characteristics
    Source Homo sapiens
    Alias Ids TPS13686, Molecular Weight 45323.88 Da.
    Residues 403 Isoelectric Point 6.87
    Sequence mahamenswtiskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidh ltdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvlanwkkkd pnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmqerdtllkalleiascl ekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyegfwedpkefaggsagqssvfqcfdvl lgiqqtaggghaaqflqdmrrymppahrnflcslesnpsvrefvlskgdaglreaydacvkalvslrsy hlqivtkyilipasqqpkenktsedpskleakgtggtdlmnflktvrstteksllkeg
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 2
    Resolution (Å) 2.30 Rfree 0.221
    Matthews' coefficent 3.00 Rfactor 0.191
    Waters 138 Solvent Content 58.70

    Ligand Information
    Ligands HEM-PIM (PROTOPORPHYRIN) x 2;NHE (4-PHENYL-1H-IMIDAZOLE) x 4
    Metals

    Jmol

     

    Protein Summary


    Ligand Summary

    Reviews

    References

     

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