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2b7o

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes. J.Mol.Biol. 354 927-939 2005
    Site TBSGC
    PDB Id 2b7o Target Id Rv2178c
    Related PDB Ids 2b70 
    Molecular Characteristics
    Source Mycobacterium tuberculosis h37rv
    Alias Ids TPS20671,15609315, O53512, 15609315, O53512, NP_216694.1 Molecular Weight 50638.68 Da.
    Residues 462 Isoelectric Point 5.46
    Sequence mnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtvpseivrlqe qlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmpvvkvariagqyakprsad idalglrsyrgdmingfapdaaarehdpsrlvrayanasaamnlvraltssglaslhlvhdwnrefvrt spagaryealateidrglrfmsacgvadrnlqtaeiyashealvldyeramlrlsdgddgepqlfdlsa htvwigertrqidgahiafaqvianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrd llppivekvqatghqviwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitg envteclggaqdisetdlagryetacdprlntqqslelaflvaemlrd
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 2
    Resolution (Å) 2.30 Rfree 0.22429
    Matthews' coefficent 3.90 Rfactor 0.18778
    Waters 336 Solvent Content 68.00

    Ligand Information
    Ligands SO4 (SULFATE) x 2;PEP (PHOSPHOENOLPYRUVATE) x 2;CE1 (O-DODECANYL) x 1
    Metals MN (MANGANESE) x 2

    Jmol

     

    Protein Summary


    Ligand Summary

    Reviews

    References

     

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